Neogenetics | |
Two
discoveries/inventions that define the Dragon Age is the lotus plasmid
and genetic editing, together defining the field of neogenetics. The
Lotus Plasmid
The
lotus plasmid was first announced in the massive patent and trademark
claims of Ikhwan Bioassay, Omicron Developments and Synbionics July 15
2035, at the early phase of the Socotra Crisis. In the press releases
it was described as a novel way of modifying the genes of adult organisms
by exploiting the unique properties of a certain class of small DNA-RNA
fragments. Within a few days it was clear that it was closely related
to the up until then unknown means used by the terrorist group Black Lotus
in the Canton Crisis and Cambodia Incident 2034. This led to the popular
name for the plasmid, although strictly speaking it is not a plasmid but
a DNA-ribozyme complex. The
lotus plasmid is able to edit the genome of any cell, and acts as an extremely
efficient genetic vector. It appears that it exploits a previously unknown
and unsuspected property of DNA coiling (the so-called emergent ribozyme
coil), becoming essentially a kind of genetic backdoor. Receptors for
the plasmid have been found with 100% conservation in all terrestrial
life, apparently encoded in some of the “emergent genes” that are just
now discovered. Once a cell has received the plasmid message, it relays
it to neighbours through adhesion bridges. Although
patent claims were filed, this was mostly symbolic and to announce that
the involved parties possessed detailed knowledge of the plasmid (the
claims would not have been regarded as valid in most jurisdictions anyway).
Since then the field of neogenetics has expanded tremendously, as partnerships
and independent works to understand and exploit the lotus plasmid has
become the hottest investment field in history. Even without genetic editing
through hosts with AM growths, it has made gene therapy orders of magnitude
more efficient. The properties of emergent ribozymes and the lotus plasmid
have been compared to genetic nanotechnology. Work
is underway of developing immunity to the lotus plasmid, but so far no
efficient methods have been found. Although antibodies can easily be developed,
the spread through tissue is pervasive and the immune system is often
one of the earliest organ systems to be affected. The existence of such
a complex system as the emergent ribozymes has led many to conclude that
terrestrial genetics has been deliberately adapted (or created); fitness
landscape and mutagenesis studies show that it is not possible to evolve
it. Since it is closely associated with the dragons, the general assumption
is that it is their creation. Another
area where much research is being done is the reliable detection and analysis
of lotus plasmids. Similar genetic fragments appear to be ubiquitious
in the biosphere, making it hard to detect plasmids of human origin. Once
a particular plasmid has been analysed it is fairly simple to device a
sniffer to signal its presence, but detection of larger classes or traces
of certain host individuals have been less successful. The field is under
fast development, and it is expected that efficient sniffing will be feasible
within a few years. Gene
editing
The
AM growth (first named after A.M., the first host) is a heavily modified
tissue that usually grows on the ventral side of the brain. It has many
properties similar to an endocrine gland like the pituiary, but the cells
are mainly modified neurons and interface heavily with the brain. It enables
the host to design, produce and react to lotus plasmids. The way this
is achieved remains enigmatic. Well developed hosts are able to not just
modify their own bodies but also affect others by the plasmids in their
breath and bodily fluids. The
AM growth is initiated by infection by the “dragon pearl plasmid”, a lotus
plasmid encoding a very complex genetic program that in some hosts lead
to the development of the AM growth. Epidemological studies have shown
that the likelihood of a growth depends on individual genetic variation,
lack of prion vaccinations and immune function. The growth is very similar
to a gliome, and can cause headaches, nausea and hallucinations merely
by its physical location. There is also a crisis once the production of
lotus plasmids begins, as the immune system will react in an autoimmune
way. There
is much research on genetic editing through neurocomputers. This would
avoid the risks of having human infected by the still largely mysterious
plasmid and would enable technological control. The results have however
been mixed, with some laboratories reporting no success and others demonstrating
significant results. The
Dragons
The
Dragons define this age, even without being near. Their looming presence
affects culture worldwide. People are trying to come to terms with the
realisations that we are not alone, that the aliens are more alien than
anything imagined and that by the end of the century, the Dragons may
be the dominant species. The
first public emergence of a Dragon was the Socotra Crisis in July-August
2035. In front of billions of viewers a seamonster dubbed “the Kraken”
attacked the bioislands outside Socotra, killing 1283 people and destroying
property worth hundreds of billions of dollars. During the struggle against
the Kraken the lotus plasmid was first used, and at one point it appeared
that it had succeeded in neutralising the lifeform. But apparently this
just enabled the Dragons to fully involve themselves: in a massive oil
upwelling and restructuring the remnants of the Kraken became the seed
of the first “dragon castle”. A few months later similar dragon castles
were emerging around nearby islands, and since then they have spread further
into the Indian Ocean. Commonly
Dragons refer to the dragon castles, but the actual entities are more
nebulous. According to revelations from various sources such as NERD,
Omicron Developments, Siripong Siripool and many others the true form
of the Dragons is ecological networks in the lithosphere, employing plasmid
interactions instead of neural activity. The dragon castles are simply
efficient “bodies” for the dragons to control Dragon
castles are enormous structures, the result of the fusion of many millions
of tons of biomass. As far as we know, they emerge from seedling creatures.
Seedlings are independent creatures, little more than larvae equipped
with glands producing large amounts of plasmids. The seedlings swim or
fly away from the parent castle, seeking out dense concentrations of biomass.
There they infect/assimilate local life, creating the typical sessile
web of a first stage colony. As the web grows, it absorbs more and more
biomass and become more motile. Second stage colonies have grown to the
size of a few hundred meters and are capable of devising new bioforms
to suit their purposes. Third stage colonies have absorbed practically
all available biomass, and begin to take on the adult form. The previous
webwork develops into a skeletal framework, covered with energy providing
“kelp” and equipped with massive siphons to filter seawater. The emerging
castle rises to the sea surface and at the same time sends down roots
deep into the seafloor, making contact with the local Dragons. A typical
dragon castle consists of a bone, chitin, cellulose or cartilage skeleton,
covered with other organs. Most of the structure is actually empty space,
filled with water or gas. Nutrient and water vessels extend along the
skeleton, transporting nutrients and plasmids to all parts and piping
filtered water from one level to another. Underwater, the view of a dragon
castle is dominated by enormous siphons filtering seawater for more building
materials and energy. Apparently a major energy source of many castles
is a biological form of OTEC, where cold deep water is pumped upward and
the energy gradient exploited. The water also provides nutrients for the
typical algae blooms surrounding the castles. The algae apparently act
as energy and nutrient collectors, and are often controlled by long filament
extending from the castle proper. The surface is often covered with variants
of biotech bamboo not unlike the standard industrial bamboo used on bioislands
(much of the components are directly copied from the islands digested
in the Socotra Crisis). Dragon
islands send down extensive roots into the ground, likely to connect to
the lithosphere Dragons. The presence of oil or other energy rich hydrocarbon
deposits is exploited; in several cases the islands dig their own oil
or gas wells, apparently extracting energy and nutrients by extensive
chambers of modified bacteria. Inside
the bones and special structures are human-derived neural materials. It
appears that there are many different neural systems, both extensive neural
networks showing signs of distributed intelligence, thick neural trunks
maintaining internal communications, spine- and brain-like growths in
the bones and the deep and well protected neurocomputer-like clusters
that likely house the main intelligence. The surface of the structure
contains sensory organs borrowed from across the animal kingdom, giving
it enormous sensory input bandwidth. Several observations of long-range
filaments conatining neurons extending along the seafloor towards other
castles have been observed, suggesting that the castles attempt to set
up fast communications links. Dragon
castles also contain extensive glands for producing plasmids, usually
in close connection with the neural clusters. These glands, apparently
giant Masterton growths, produce plasmids used both for reprogramming
and reshaping the castle, assimilating more biomass and the long-range
spread in seawater.
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